The ICF Core Set development project for multiple sclerosis (MS) was a cooperative effort between Valens Rehabilitation Centre (Switzerland), the ICF Research Branch, the World Health Organisation (WHO), the Multiple Sclerosis International Federation (MSIF) and the International Society of Physical Medicine and Rehabilitation (ISPRM). The aim of the project was the development of ICF Core Sets to comprehensively describe functioning and disability of individuals with MS.

To describe and rate the consequences of spinal cord injury (SCI), a wide range of measures has been used. Unfortunately, there is a wide variation in currently available measures, including variation in underlying dimensions and terminological confusion as well as difficulty in carrying over data from one episode of care - emergency, medical, rehabilitative, outpatient and community clinical care - to another episode of care involving a different clinical focus. To address this clinical information need, the project aimed to develop ICF Core Sets to comprehensively describe functioning and disability of individuals with SCI.

A major issue for professionals working with traumatic brain injury (TBI) concerns the large variation in currently available measures to address function and disability in TBI. There is little standardization in the use of these instruments and therefore, comparison of data is quite difficult. The objective of the ICF Core Set development project for persons with TBI was to identify relevant categories which comprehensively describe and measure the spectrum of limitations in functioning of persons with TBI. The project was a collaborative effort between the Guttmann Institute, the ICF Research Branch, the World Health Organisation (WHO) and the International Society of Physical Medicine and Rehabilitation (ISPRM). The enormous organization of completing all 4 preliminary studies culminating in the consensus conference which took place in Barcelona from 26-28 March 2010 was under the leadership of the Brain Injury Unit at the Guttmann Institute.